NAD+Nicotinamide Adenine Dinucleotide
NAD+ is the core coenzyme in cells. As the NAD+/NADH redox pair, it is widely involved in energy metabolism, DNA repair and cell homeostasis regulation. In view of its endogenous level decreasing with age, NAD+ has become a focus functional component in the field of healthy aging and metabolic management.
- CAS53-84-9
- Product QualityActual measurement by CTI, Intertek, Eurofins and other international institutions
- SafetyToxicological safety assessment
- CertificationsFSSC22000, ISO9001, HALAL, Kosher authoritative certification
Healthy Aging Management
Supports cellular energy metabolism
Activates longevity proteins Sirtuins
Helps repair DNA damage
Regulates immunity and cell signaling
Basic Information
NAD+ is a vital core functional coenzyme for the human body. It is widely involved in the body's energy metabolism, mitochondrial repair, DNA damage repair, redox regulation and cell homeostasis maintenance. It is a core functional raw material in the field of general health, anti-aging and body function maintenance. The endogenous NAD+ content of the human body will naturally decrease with age, which directly leads to a decrease in cell metabolism efficiency and a decline in vitality. It is an important cause of aging and decline in human body functions.
Hygieia Biotech provides NAD+ and its full range of precursor raw materials, with excellent purity, stable physical and chemical properties, and strong formula compatibility. It is widely used in the research and development of multi-category formulas such as dietary supplements, functional foods, and high-end skin care. It also supports sample customization and batch supply to fully meet customer production and research and development needs.
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Product name
Nicotinamide Adenine Dinucleotide (NAD+)
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English name
Nicotinamide Adenine Dinucleotide
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CAS number
53-84-9
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Nickname
NAD+, beta-Nicotinamide adenine dinucleotide
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Molecular formula
C21H27N7O14P2
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molecular weight
663.40
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Purity
99%
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Appearance
white powder
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solubility
soluble in water
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Packaging specifications
1kg/bag; 25kg/barrel
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Customized ODM services
Available upon request
Product Applications
Suggested Usage Reference
The application reference range of NAD+ common formulations can be designed around 150-300 mg/day. The specific addition amount needs to be comprehensively evaluated based on product positioning, dosage form design, compounding plan, target market regulations, and finished product specification requirements.
Popular Formula References
- NAD+ NMN, PQQ, Coenzyme Q10
- Efficacy: Supports the NAD+ metabolic system, maintains mitochondrial function, and improves cellular energy levels.
Recommended Dosage Forms
capsule
tabletApplication Scenarios
cellular energy metabolism
NAD+ (nicotinamide adenine dinucleotide) is the core coenzyme present in all living cells. As the "electronic currency" of the energy metabolism network, it plays an irreplaceable role in the process of converting food into cellular fuel. During glycolysis, the Krebs cycle, and mitochondrial oxidative phosphorylation, NAD+ accepts electrons and is reduced to NADH, which then passes the electrons to the electron transport chain, driving the formation of a proton gradient that ultimately generates ATP - the cell's direct energy source - via ATP synthase. Sufficient NAD+ can stabilize the operation of the mitochondrial respiratory chain, improve cellular energy conversion efficiency, and continuously empower the daily physiological activities of the human body.
DNA damage repair
NAD+ is an essential substrate for the poly ADP-ribose polymerase (PARP) family. PARP1 is a key early response protein in the DNA damage response. When cells are attacked by oxidative stress, ultraviolet light, or endogenous metabolic byproducts, causing DNA single-strand breaks, the PARP enzyme is activated, consuming NAD+ to transfer ADP-ribose units to target proteins, initiating base excision repair and other processes, which is crucial for maintaining genome integrity.
Longevity protein regulation
NAD+ is an essential co-substrate of the Sirtuin protein family (SIRT1–SIRT7), which is often referred to as the “longevity protein”. Sirtuins rely on NAD+ to complete deacylation modification and regulate gene expression, metabolic homeostasis and cellular aging process. Studies have shown that NAD+ levels decrease in multiple tissues during aging and are associated with multiple age-related physiological decline phenotypes. Therefore, ensuring sufficient NAD+ reserves can support Sirtuin-dependent regulatory functions and help maintain cellular homeostasis.
Quality & Documentation
- Product Specification / TDSRequest
- Eurofins / Third-party Analytical ReportRequest
- Batch Certificate of Analysis (COA)Request
- Safety Data Sheet (MSDS / SDS)Request
- FSSC 22000 & HACCP Food Safety CertificationRequest
- ISO 9001 Quality Management CertificationRequest
- FDA Registration and DMF / Compliance SupportRequest
Contact our team for specifications, batch documents, regulatory support, samples, and quotations.
Request DocumentsFrequently Asked Questions
Q1: What is the difference between NAD+, NMN and NR?
NAD+ is the core coenzyme that directly acts on the human body. NMN and NR are both high-quality endogenous precursors of NAD+, which can effectively increase the body's NAD+ reserves and assist cell energy metabolism and repair.
Q2: What is the difference between NAD+ and NADH?
NAD+ and NADH are redox forms that exist in pairs in cells and jointly maintain cellular redox homeostasis. NAD+ is the oxidized type, which mainly activates longevity proteins, initiates DNA repair, and regulates cell aging. It is the core form of cell maintenance; NADH is the reduced type, mainly involved in mitochondrial energy synthesis and replenishing body energy. The two complement each other and work together to ensure cellular metabolic vitality and physiological homeostasis.
Q3: Does Hygieia Biotech provide NAD+ samples?
Sample support can be provided according to customer needs. Customers can contact Hygieia Biotech to obtain samples, specifications, COA, TDS, MSDS and quotation plans.
Q4: How to get a quotation?
Customers can submit information such as target product direction, dosage form, expected addition volume, procurement specifications, target market, order quantity and whether ODM services are needed, and Hygieia Biotech will provide customized quotation plans based on needs.
Nicotinamide Riboside Chloride (NR-Cl)
Reduced β-Nicotinamide Mononucleotide (β-NMNH)
Nicotinamide Riboside Hydrogen Malate (NRHM)
NoticeThis content is provided for general physiological metabolism and dietary nutrition education only. It is not medical efficacy advertising and does not replace medication or professional medical care.
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