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David Sinclair’s 2024 REVISED Longevity Supplement Protocol

David Sinclair’s 2024 REVISED longevity Supplement Protocol

As you delve into longevity and health optimization, staying informed about leading experts’ latest research and updates is crucial. I’ve recently refined my supplement regimen based on current scientific findings and ongoing experiments. In this journey towards a healthier, more vital life, I’ve decided to adjust the intake of certain compounds and introduce new ones […]

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Trigonelline Powder Supplement: A Novel NAD Precursor Increases NAD, Improves Muscle Function, And Extends Lifespan

Trigonelline Powder Supplement A Novel NAD Precursor

Trigonelline powder, also known as methyl nicotinic acid—shows remarkable promise in enhancing intracellular NAD levels, muscle function, and longevity. The noticeable stability of this compound compared to NMN or NR posits it as a potentially superior candidate for supporting healthy aging. Their collaborative efforts, bridging academia and industry, have culminated in exciting discoveries that will

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NAD+ Supplementation Hinders STING-Triggered Senescence in CD8+ T Cells Through Mitochondrial Homeostasis Enhancement

NAD+ Supplementation Hinders STING-Triggered Senescence in CD8+ T Cells

Researchers Bin Ye, Ning Ma, and Yanfen Zhang from Harbin Medical University investigated whether improving mitochondrial homeostasis could alleviate the aging phenotype. Their findings demonstrated that mitochondrial dysfunction and a senescence-associated secretory phenotype (SASP) are present in aged T cells and tumor-bearing mice. Enhancing NAD+ levels through NMN supplementation promotes mitochondrial autophagy, preventing cellular aging

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L-Ergothioneine Quality Standard and Detection Method Issued by China Chamber of Commerce for Import and Export of Medicines and Health Products (CCCMHPIE)

L-Ergothioneine Quality Standard

On Dec 15, 2024, the China Chamber of Commerce for Import and Export of Medicines and Health Products (CCCMHPIE) released the raw material L-Ergothioneine Quality Standard and Detection Method. The CCCMHPIE follows national standardization procedures by China’s “Standardization Law” and “Group Standards Management Regulations” and has also announced group standards for “Tribulus Terrestris Extract,” “Solanum

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Fisetin Source: Chemical Constituents of Cotinus Coggygria Scop. Extract and Their Pharmacological Activities

Chemical Constituents of-Cotinus Coggygria Scop. Extract

Cotinus coggygria Scop., commonly known as smoketree or Japanese fruit wax tree, is a plant found in southern Europe, Iran, Pakistan, northern India, and many provinces in China. It is often used for soil and water conservation and landscaping due to its ornamental qualities. The chemical constituents of Cotinus coggygria Scop. Extracts have garnered significant

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17 Best Telomere Supplements to Naturally Increase Telomere Length in 2024

Telomere Supplements

Telomere supplements are increasingly noted for their possible benefits on aging and lifespan extension. Telomeres, the protective caps of chromosomes, gradually diminish with aging. This shortening is associated with various age-related diseases and even premature death. Scientists have been researching ways to lengthen telomeres, and several supplements have emerged as potential solutions. The process of

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Telomere Length and Longevity: Unlocking the Secrets to Aging

Telomere Length and Longevity

Telomere length and longevity are closely correlated, as telomeres are regarded as a “biological thermometer” that reflects an individual’s biological state at a certain point in life. As one ages, the caps that protect the ends of linear chromosomes, also called telomeres, tend to shorten. This shortening can lead to cellular senescence and contribute to

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Top 20 Best Senolytic Supplement Ingredients in 2024: A Comprehensive Guide

20 Best Senolytic Supplement Ingredients

Senolytic supplements have gained increasing attention recently for their potential to combat cellular aging and promote overall health. These supplements work by targeting senescent cells, also known as “zombie cells,” which are cells that have stopped dividing and can accumulate with age, leading to various age-related diseases. As researchers delve deeper into senolytics, many ingredients

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Мitochondria Supplements and Its Impact on Longevity

Mitochondria and longevity

Мitochondria Supplements are important for anti-aging. How fast we age, how old we are, and how long our lifespan will depend on ourselves. This has been proven by science in many years of research. Numerous scientific studies have shown that many age-related degenerative diseases can be avoided. They show that 80-90% of degenerative diseases are

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