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Which is the Best NMN Forms: Powder, Capsule, Softgel, Nasal Spray, Sublingual Tablets, or Liposomal nmn?

NMN forms

NMN supplementation plays an important role in the body and offers many health benefits. As one of the best precursors for increasing NAD+ levels within the body, there are various and different NMN forms available on the market. Depending on your needs and favorite type of NMN to consume, innovative forms are developed such as powder, capsule, softgel, nasal spray, sublingual tablets, and liposomal NMN. Every form has pros and cons, which differentiate in the purity, effectiveness, bioavailability, dosage, and other factors. For better understanding, and to make it easier for you to choose, in addition we will discuss the different forms of NMN supplementation.

Different NMN forms

NMN supplements came in various forms, including:

NMN powder

NMN powder is the most abundant form of NMN supplementation. It is the most stable pharmaceutical grade for boosting NAD+ levels. Its purity reaches above 99%. NMN as a powder is directly absorbed through the blood, which means the effect is more rapid. This will increase bioavailability as well. With this way of administration, NMN avoids digestion in the gastrointestinal tract, so it can be faster delivered in the blood. 

NMN capsule

NMN capsule is highly stabilized and has high bioavailability. The purity may range from 98-99%. Capsules tend to break down in the digestive system, and then be absorbed, and metabolized through the bloodstream to the targeted place. Most NMN capsules are without odor or unpleasant taste, so everyone can consume them. However, for some people can be hard to swallow. They are more sensitive to environmental conditions, such as humidity. That’s why the manufacturer must ensure that they are shelf-stable when packaged and stored. Also, sometimes you need to take more capsules to achieve the perfect dosage.

NMN softgel

NMN sotfgel is a kind of capsule, which is wider, and often the substance is suspended in gelatin. They are easy to digest, thus can be easily absorbed. Because they have soft sheld, some people find them easier to administrate. They are stable NMN form, with high purity, and bioavailability. According to the manufacturer, NMN softgel can vary in shape. However, they can be comfortably swallowed. To achieve maximum absorption, NMN is put in gelatin capsules that are slowly dissolved.

NMN nasal spray

If you want to buy NMN nasal spray, the technique of how you use the spray is very important in order to achieve the desired effects. Usually, the NMN nasal spray contains a liquid form of NMN. Using NMN nasal spray makes quick and better results because avoids the bloodstream and GI and goes directly to the brain. It is the best option to minimize drugs administration and to reduce the side effects they may cause. Also, by taking NMN nasal spray you may achieve higher bioavailability and effects at the same or similar dosage as typical drug dosage intake.

NMN sublingual tablets

NMN sublingual tablets mean placing them under your tongue for better absorption into the bloodstream. The administration is fast and the results are rapid and with the maximum potency. The absorption is through the mucous membrane under the tongue, which has many capillaries for substances to move into the bloodstream. The bioavailability of taking NMN sublingually is 30%, where the other percent go into the GI to be broken down.

Liposomal NMN

Liposomes are made of phospholipids, which mimic the cell membrane within the body. They help to deliver the NMN to the desired cells much effectively through the bloodstream. This increases absorption and bioavailability. Liposomal NMN offers better absorption because it is not broken down in the gut by the stomach acid. Therefore, taking liposomal NMN supplements provides more powerful and rapid effects.


The reduced form of NMN is NMNH. Studies show that taking NMNH has a greater effect in increasing NAD+ levels in the blood than NMN. NMNH is better absorbed in the body to boost NAD+ levels. One study published that injected NMNH was stable up to 24 hours, compared to NMN which was stable only for the first 4 hours. We can conclude that NMNH supplementation is a much more potent form for increasing NAD+ levels within the cell. However, the cost of NMNH is high, as well as can vary based on the manufacturing methods, and the stock is in short supply.

NMN has become the most popular supplement for anti-aging on the market. Many researched studies claim its effectiveness and significant results. Therefore, there are abundant forms of NMN supplements to buy. The most popular form of NMN supplement available on the market is in capsules.

nmn powder vs capsule

The powder has the potential for quicker absorption since it can be taken sublingually (under the tongue), allowing it to enter the bloodstream more directly. This bypasses the digestive system, which may lead to a more immediate increase in NAD+ levels. Capsules, on the other hand, must go through the digestive tract, which could potentially delay absorption. However, the convenience of capsules makes them a popular choice for many users. They are easy to swallow, have a longer shelf life, and the dosage is straightforward, eliminating the need for measurement.

nmn sublingual vs oral

Sublingual administration of NMN, either through powder or dissolvable tablets placed under the tongue, allows for direct absorption into the bloodstream via mucous membranes. This method can lead to quicker increases in NAD+ levels since it bypasses the digestive system and may prevent NMN degradation by gastrointestinal enzymes, offering a potentially more effective way to boost NAD+.

Conversely, oral administration involves swallowing NMN capsules or tablets, which then travel through the digestive system. This traditional approach is slower as it requires absorption through the gut before entering the bloodstream. Despite the risk of NMN breakdown during digestion, oral supplements are popular due to their ease of use and convenience in daily routines. Sublingual NMN is less common but is gaining attention for its potential for faster and more direct absorption.

Which form of NMN supplement is the best to choose?

When choosing the best form of NMN supplementation, you should pay attention to several things. Not every NMN supplement sold on the market is effective. Because the hype about NMN is real, many brands offer low-purity NMN products or some even don’t contain NMN at all. The level of purity, bioavailability, potency, and stability are some of the important factors you should consider when buying NMN supplements. Of course, the cost plays its role too.

According to the studies, NMNH supplementation is far more efficient and faster than other NAD+ precursors, but unfortunately, the price is high. Therefore, taking liposomal NMN capsules is the next potent form. This technology is more economic, which leads to highly effective, stable, high purity, enhanced bioavailability, and strong NMN supplement.

What kind of NMN does David Sinclair use?

Dr. David Sinclar, a professor at Harvard University, focuses on molecules that impact the anti-aging process, such as NMN. He takes 1 gram of oral NMN capsules in the morning. He believes that taking NMN for anti-aging, and other aging-related conditions, is better than any other NAD+ precursors.

About us

Hygieia Biotechnology is a professional manufacturer that offers raw bulk products for use as supplements, cosmetics, and medicine. From formula development, through dosage analysis, formula evaluation, testing, packaging screening to finished product delivery. All products are tested by accredited third-party labs to ensure purity, identity, and potency. In addition, they are non-toxic, safe to use, which meets the standards of the manufacturing process according to GMP.

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